Buy 5-MeO-DMT Online – Bulk Supply
5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) is a naturally occurring psychedelic compound belonging to the tryptamine class. It is found in various plant species and the venom of the Colorado River toad (Incilius alvarius). In recent years, 5-MeO-DMT has garnered attention for its unique psychoactive properties and potential therapeutic applications.
Pharmacology and Mechanism of Action
5-MeO-DMT is a potent serotonin receptor agonist, with a higher affinity for the 5-HT₁A receptor compared to the 5-HT₂A receptor. This receptor profile contributes to its distinct psychedelic effects, which differ from those of other tryptamines like DMT. The compound is approximately 10–20 times more potent than DMT in humans American Chemical Society Publications.
Effects and Duration
The effects of 5-MeO-DMT are typically short-lived, with the peak experience lasting between 20 to 45 minutes. Users often report intense, introspective experiences that can include alterations in perception, a sense of unity, and profound emotional insights. The duration and intensity of effects can vary based on the method of administration, dosage, and individual sensitivity.
Safety and Tolerability
Clinical studies have indicated that 5-MeO-DMT has a favorable short-term safety and tolerability profile. In a review of clinical trials, no serious adverse events (SAEs) were reported, and no participants withdrew due to adverse effects PubMed. However, as with any psychoactive substance, individual reactions can vary, and it is essential to approach its use with caution and under appropriate supervision.
Therapeutic Potential
Emerging research suggests that 5-MeO-DMT may have therapeutic potential, particularly in the treatment of mood disorders. A Phase 1/2 trial investigating the inhaled GH001 formulation of 5-MeO-DMT in patients with treatment-resistant depression found that the compound was well-tolerated and associated with improvements in depressive symptoms Frontiers. These findings are preliminary, and further studies are needed to fully understand the therapeutic applications of 5-MeO-DMT.
Conclusion
5-MeO-DMT is a potent psychedelic compound with unique pharmacological properties and a promising safety profile. While current research is in the early stages, the compound’s potential therapeutic applications warrant further investigation. As with all research chemicals, it is crucial to approach 5-MeO-DMT with due diligence, ensuring that studies are conducted ethically and with appropriate oversight.
Product Details Table
| Attribute | Details |
|---|---|
| Brand / Manufacturer | GH Research, Dublin, Ireland |
| Composition / Ingredients | 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) |
| Concentration / Volume | Varies; typically administered in microgram to milligram doses |
| Duration of Effects | Approximately 20–45 minutes |
| Indications / Usage Areas | Investigational use in clinical trials for mood disorders |
| Injection Depth / Method | Administration methods vary; commonly inhalation or vaporization |
| Shelf Life | Not specified; stability data under investigation |
| Storage Conditions | Store in a cool, dry place; protect from light and moisture |
| Package Contents | Typically supplied as a crystalline powder or in solution |
| Country of Origin | Ireland |
| Licensing / Certification | Investigational New Drug (IND) status in clinical trials |
| Safety Notes / Side Effects | Short-term safety profile favorable; adverse effects may include anxiety, nausea, or confusion in some individuals |
